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What antibiotics cause Steven Johnson Syndrome?

What antibiotics cause Steven Johnson Syndrome?

The medicines that most commonly cause Stevens-Johnson syndrome are:

  • allopurinol.
  • carbamazepine.
  • lamotrigine.
  • nevirapine.
  • the “oxicam” class of anti-inflammatory drugs (including meloxicam and piroxicam)
  • phenobarbital.
  • phenytoin.
  • sulfamethocazole and other sulfa antibiotics.

Can sulfa drugs cause Steven Johnson Syndrome?

Medications most likely to cause Stevens-Johnson syndrome include: Antibacterial sulfa drugs. Anti-epileptic drugs, including phenytoin (Dilantin®), carbamazepine (Tegretol®), lamotrigine (Lamictal®), and phenobarbital (Luminal®). Allopurinol (Aloprim®, Zyloprim®), a drug used to treat gout and kidney stones.

Which drug has a high risk of Stevens-Johnson syndrome?

Conclusions: The use of antibacterial sulfonamides, anticonvulsant agents, oxicam NSAIDs, allopurinol, chlormezanone, and corticosteroids is associated with large increases in the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis.

Can vancomycin cause Steven Johnson Syndrome?

Serious cutaneous reactions to vancomycin, however, have been uncommon. Cessation of vancomycin treatment in our patient led to eventual resolution of her symptoms. Conclusions: Vancomycin is a potential causative agent of Stevens-Johnson syndrome.

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Does Bactrim have sulfa in it?

Sulfamethoxazole / trimethoprim (Bactrim, Sulfatrim), a sulfa combination drug that can be taken in liquid or pill form for many types of infections.

Which drugs are most associated with Stevens-Johnson syndrome?

Anti-gout medications,such as allopurinol

  • Medications to treat seizures and mental illness (anticonvulsants and antipsychotics),with added risk if you also undergo radiation therapy;
  • Pain relievers,such as acetaminophen (Tylenol,others),ibuprofen (Advil,Motrin IB,others) and naproxen sodium (Aleve)
  • What are the stages of Steven Johnson syndrome?

    Often, it begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters. Then the top layer of the affected skin dies, sheds and then heals. Stevens-Johnson syndrome is a medical emergency that usually requires hospitalization.

    What caused Steven Johnson syndrome?

    Stevens-Johnson Syndrome is a life-threatening skin disorder wherein it causes separation of the epidermis to the dermis as a result of cell death. Stevens-Johnson syndrome is a result of hypersensitivity reaction in the skin and mucous membranes as a result of immune-complex mediation.