Why product is major in preparation of P Bromoacetanilide?

because it is a bulkier group the substitution at the ortho position scarcely occurs, yielding the para mono-substituted compound as the major product (Scheme 5.1. 8.3). This compound, p-bromoacetanilide, already has the substitution pattern of the benzene ring that is desired for the final product.

What is para Bromoacetanilide?

Molecular Formula. C8H8BrNO. Synonyms. 4′-Bromoacetanilide. 103-88-8.

What takes place during the electrophilic aromatic substitution reaction?

In electrophilic aromatic substitutions, a benzene is attacked by an electrophile which results in substition of hydrogens. However, halogens are not electrophillic enough to break the aromaticity of benzenes, which require a catalyst to activate.

Why bromination of acetanilide occur at para position?

Bromination of acetanilide occurs at the para position due to the amine substituent this substituent provides resonance stabilization to the carbocations created by ortho and para addition. Since the amine provides steric hinderance at the ortho position, bromination acetanilide occurs at the para position.

Which reaction is involved in the preparation of P Bromoacetanilide from acetanilide?

Principle: p-bromoacetanilide is prepared by bromination process. Mono substituted products of primary amine cannot prepared easily by direct action of a reagent. Bromination of acetanilide gives para brominated acetanilide mainly, because amino group of acetanilide is protected by acetyl group.

What is the formula of para Bromoacetanilide?

C8H8BrNO
4′-Bromoacetanilide, 98\%, Thermo Scientific

What is the literature melting range OC for para Bromoacetanilide?

It was found to have a melting point in the range of 167 – 170 oc which confirmed it’s identity as p-bromoacetanilide, whose melting point is quoted as 166 – 170 oc. 20.5 mmol of this were obtained out of a possible 35.4mmol, which is how much acetanilide we began with, generating a yield of 57.9\% for this stage.

Why para product is major in electrophilic substitution reaction?

When electrophilic substitution reaction takes place, and the ortho and para products are formed then among them para is considered as the major product and ortho as a minor product. The reason behind this is the steric hindrance.

What is the role of glacial acetic acid in the preparation of P-Bromoacetanilide from acetanilide?

Glacial acetic acid is a polar protic solvent that can dissolve acetanilide. In acetic acid, bromine is ionized to bromonium ion to a lesser extent as…

Why do aromatic hydrocarbons undergo electrophilic substitution reaction Class 11?

Explanation: Aromatic hydrocarbons have pi electrons but does not undergo addition reaction because resonance of compound get altered. We know that aromatic compound is stable due to resonance. So, the aromatic hc prefers substitution reaction and due to its nucleophile nature, it attracts electrophile.