Is it OK to eat grapefruit with prednisone?

Grapefruit juice can be one of the factors leading to intraindividual variability in the pharmacokinetics of cyclosporine. Grapefruit juice had no significant effect on the metabolism of prednisone or prednisolone.

What medications have a bad interaction with grapefruit?

Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).

Does grapefruit juice affect steroids?

Steroids. Some steroids like budesonide (Pulmicort) and methylprednisolone (Medrol) can reach higher blood levels if taken with grapefruit juice. This can dangerously raise your blood sugar levels and blood pressure, and cause other serious and sometimes long-lasting effects of too much steroids in the body.

Why does grapefruit mess with medications?

Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body.

Does grapefruit interfere with the pill?

Theoretically, consuming grapefruit with birth control pills might increase the estrogen levels in your blood. This shouldn’t lower the effectiveness of your birth control, but it might increase the chances for side effects like breast tenderness, nausea, changes in uterine bleeding, blood clots, or breast cancer.

Is it safe to eat grapefruit with prednisone?

The effect of grapefruit juice on cyclosporine and prednisone metabolism in transplant patients. Grapefruit juice can be one of the factors leading to intraindividual variability in the pharmacokinetics of cyclosporine. Grapefruit juice had no significant effect on the metabolism of prednisone or prednisolone.

Does grapefruit interfere with prednisone?

Possible changes in your diet, medicine, or dosage should be discussed with your doctor or pharmacist. Grapefruit juice decreases the ability of your gut to process methylprednisolone. The level of this drug can increase in your blood and cause more side effects than usual.

What can you not eat with prednisone?

Avoiding refined carbohydrates, excess salt and excess calories may help to prevent some of the side effects of prednisone. A smart first step is to avoid packaged foods and fast food, since they contain large amounts sugar, salt and calories.

What foods to eat with prednisone?

Choose lean meats, poultry and fish. Avoid fried foods and foods with extra oil, butter, margarine, mayonnaise and the like. Eat foods rich in calcium. Prednisone may alter your body’s ability to use calcium.