What are parenchymal cells?

Parenchymal cells: cells that occupy most of the tissue volume, express functions that are definitive for the tissue, and interact with all other cell types to facilitate the expression of differentiated function. • Mesenchymal cells (such as fibroblasts and smooth muscle cells) are present in all tissues.

What are parenchymal cells in the liver?

The parenchymal cells of the liver are hepatocytes. These polygonal cells are joined to one another in anastomosing plates, with borders that face either the sinusoids or adjacent hepatocytes.

What are the main cells of the liver called?

Four major liver cell types—hepatocytes (HCs), hepatic stellate cells (HSCs), Kupffer cells (KCs), and liver sinusoidal endothelial cells (LSECs)—spatiotemporally cooperate to shape and maintain liver functions.

What types of tissues are in the liver?

The normal liver contains typical connective tissue proteins (collagens, structural glycoproteins and proteoglycans) not only in vessel walls, perivascular areas and in the capsule, but they occur also in small amounts in the parenchyma, mainly in the space of Disse along the sinusoidal walls.

Where are parenchyma cells?

Parenchyma cells occur in the form of continuous masses as homogeneous parenchyma tissues e.g. in pith and cortex of stems and roots, mesophyll of leaves, the flesh of succulent fruits and in the endosperm of seeds.

What is the main function of parenchyma cells?

The unifying characteristic of all parenchyma cells is that they are living at maturity and capable of cell division, giving them important roles in regeneration and wound healing. Other key functions of these cells include photosynthesis, storage, secretion and transport.

What does parenchymal liver disease mean?

Gastroenterology. Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis.

What is parenchymal liver disease?

Diffuse parenchymal liver diseases, including hepatic steatosis, fibrosis, metabolic diseases, and hepatitis cause chronic liver injury and may progress to fibrosis and eventually hepatocellular carcinoma.

What are liver lobules?

The lobules of liver, or hepatic lobules, are small divisions of the liver defined at the microscopic (histological) scale. The hepatic lobule is a building block of the liver tissue, consisting of a portal triad, hepatocytes arranged in linear cords between a capillary network, and a central vein.

Why is my liver inflamed?

You can develop an inflamed liver because of excessive consumption of alcohol. The liver can also become swollen from processing too many other toxins, such as excess amounts of acetaminophen or other supplements and medications. Cirrhosis is the formation of scar tissue on the liver because of alcoholism or hepatitis.