Why are some aromatic compounds carcinogenic?

Aromatic compounds are frequently carcinogenic because their physical molecular structures frequently contain five and six carbon rings.

Are aromatic hydrocarbons carcinogenic?

Persons especially at risk occupationally are those engaged in thermal processing of oil shale, coal, and heavy residual petroleum. It has been shown that polycyclic aromatic hydrocarbons require metabolic activation before they can act as mutagens or carcinogens.

What are the aromatic compound that is being considered carcinogenic?

Benzo(a)pyrene, an aromatic hydrocarbon produced in small amounts by the combustion of organic substances, contains five fused benzene rings. Like several other polycyclic aromatic hydrocarbons, it is carcinogenic.

Why are polycyclic aromatic hydrocarbons carcinogenic?

Carcinogenicity. Although unmetabolized PAHs can have toxic effects, a major concern is the ability of the reactive metabolites, such as epoxides and dihydrodiols, of some PAHs to bind to cellular proteins and DNA [1].

Do aromatic hydrocarbons undergo substitution reactions?

Aromatic compounds or arenes undergo substitution reactions, in which the aromatic hydrogen is replaced with an electrophile, hence their reactions proceed via electrophilic substitution. The order of substitution on aromatic compounds is governed by the nature of substituents present in the aromatic ring.

Which is not an aromatic hydrocarbon?

Solved Examples Solution: Cyclopentadiene is a non-aromatic compound. Cyclopentadiene does not follow Huckel’s Rule, as it has sp3 carbon in the ring.

Why polycyclic aromatic hydrocarbons PAH would be considered harmful?

Long-term health effects of exposure to PAHs may include cataracts, kidney and liver damage, and jaundice. Repeated skin contact to the PAH naphthalene can result in redness and inflammation of the skin. Breathing or swallowing large amounts of naphthalene can cause the breakdown of red blood cells.

What are some other hydrocarbons that are also causing concern due to their environmental or health impact?

Methane and chlorofluorocarbons are two hydrocarbons that can drastically alter the atmosphere. Methane oxidizes into carbon dioxide (CO2), increasing the amount of CO2 in the atmosphere and adding to the greenhouse effect and global warming.

Are PAH carcinogenic?

The carcinogenicity of certain PAHs is well established in laboratory animals. Increased incidences of lung, skin, and bladder cancers are associated with occupational exposure to PAHs. Epidemiologic reports of PAH-exposed workers have noted increased incidences of skin, lung, bladder, and gastrointestinal cancers.

Why do aromatic compounds not undergo addition reactions?

Although aromatic compounds have multiple double bonds, these compounds do not undergo addition reactions. Their lack of reactivity toward addition reactions is due to the great stability of the ring systems that result from complete π electron delocalization (resonance).

Why do aromatic compounds undergo substitution?

Explanation: The aromatic structure provides significant additional stability to the molecule. Substitution reactions allow the aromatic structure to remain, whereas additions would change the C-C bonding away from being aromatic.

Which of the following compound is not an aromatic compound?

Benzoic acid, toluene, and chlorobenzene are aromatic compounds. Structure of benzoic acid, toluene, and chlorobenzene is given below: Ethyl ethanoate is an ester having the functional group -COO. It is not an aromatic compound.