What medications make restless leg syndrome worse?

certain medications that may aggravate RLS symptoms, such as antinausea drugs (e.g. prochlorperazine or metoclopramide), antipsychotic drugs (e.g., haloperidol or phenothiazine derivatives), antidepressants that increase serotonin (e.g., fluoxetine or sertraline), and some cold and allergy medications that contain …

Can hydroxyzine cause restlessness?

Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as restlessness, confusion, hallucinations), shaking (tremor), difficulty urinating, fast/irregular heartbeat.

Do antihistamines worsen restless leg syndrome?

A number of medications can make RLS worse. In particular, anti-nausea drugs and sedating antihistamines (like Benadryl) block the brain’s dopamine receptors, causing restless legs symptoms. Antidepressants that increase serotonin and antipsychotic medications can also aggravate the condition.

Does hydroxyzine help restless leg syndrome?

Hydroxyzine, a medication with sedative properties,6-8 had been effective on RLS symptoms in Case 1. Since sleep disturbances and anxiety were present in both Case 2 and Case 3, we decided to administer the same drug in both patients at the dosage of 25mg at bedtime, before trying any alternative treatment for RLS.

What are the most common side effects of hydroxyzine?

Drowsiness, dizziness, blurred vision, constipation, or dry mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Does Benadryl help with restless legs?

No natural or over-the-counter (OTC) medications consistently improve RLS. OTC sleeping medicines such as Benadryl (an antihistamine) and melatonin may actually worsen symptoms.

Can you take hydroxyzine every night?

Hydroxyzine may be taken every day at regular times or on an as needed (“PRN”) basis. Typically, your healthcare provider will limit the number of doses you should take in one day.

Do muscle relaxers help restless leg syndrome?

While muscle relaxants are primarily used for muscle spasms and back pain, they are also prescribed for RLS. Low doses of muscle relaxants are sometimes used in conjunction with opioid analgesics and sleep medications to help combat RLS.