Do RNA viruses replicate in the cytoplasm?
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Do RNA viruses replicate in the cytoplasm?
Schematic representation of a generic replication strategy used by a positive-strand RNA virus showing localization of the capsid protein to the nucleolus. The virus enters the cell and the genome is uncoated and then translated by ribosomes to produce the viral RNA-dependent RNA polymerase (RdRp).
Where do most RNA viruses multiply?
Replication between viruses is varied and depends on the type of genes involved. Most DNA viruses assemble in the nucleus; most RNA viruses develop solely in cytoplasm. Viral populations do not grow through cell division, because they are acellular.
Where do most RNA viruses replicate their genome?
Replication occurs in the cytoplasm. The virus codes for its own RdRp, which converts the (−) stranded RNA into (+) RNA template strands.
Which RNA viruses replicate in the cytoplasm?
All RNA viruses replicate in cytoplasm, except Orthomyxoviruses and Retroviruses that have replicative stages in nuclei. All DNA viruses require a nucleus, except Poxviruses that can replicate in the cytoplasm.
How do viruses replicate in the cytoplasm?
Usually, the viral genome is replicated using the host cell DNA polymerase, and the viral genome is transcribed by the host cell RNA polymerase. The resulting transcripts carrying information encoding viral proteins is then transported to the cytoplasm and seen as a template by the host cell ribosomes.
Does RNA replicate itself?
RNA That Replicates Itself Indefinitely Developed For First Time. The scientists have synthesized for the first time RNA enzymes that can replicate themselves without the help of any proteins or other cellular components, and the process proceeds indefinitely. …
Why do RNA viruses need to supply some of their own enzymes for replication?
RNA viruses require their own supply of certain enzymes because host cells lack enzymes that can replicate the viral genome.
How do sense RNA viruses replicate?
RNA viruses replicate their genomes using virally encoded RNA-dependent RNA polymerase (RdRp). The RNA genome is the template for synthesis of additional RNA strands. The number of proteins in the replicase complex differs among virus families. There may also be a requirement for host cell proteins.