Which contaminants do you expect to be present in the final aspirin product?
Table of Contents
- 1 Which contaminants do you expect to be present in the final aspirin product?
- 2 What is the byproduct of the reaction between acetic anhydride and salicylic acid?
- 3 How is salicylic acid converted into aspirin?
- 4 How is salicylic acid produced?
- 5 What happens when salicylic acid reacts with acetic anhydride followed by acid hydrolysis?
- 6 How is salicylic acid converted into aspirin give equation?
Which contaminants do you expect to be present in the final aspirin product?
The aspirin produced in this activity is not pure. It is often contaminated with salicylic acid, acetic acid, and/or sulfuric acid. Students should not taste their aspirin. Fill the 50-mL buret with acetic anhydride.
What does a resulting deeper color than that of the 0.15\% salicylic acid indicates?
The more salicylic acid in the sample, the deeper the color. This indicates that the product is impure or that decomposition has taken place. The maximum salicylic acid allowed in commercially prepared aspirin products is 0.15\%.
What is the byproduct of the reaction between acetic anhydride and salicylic acid?
Aspirin is acetyl salicylic acid. It can be synthesized with the reaction of salicylic acid and acetic anhydride. Aspirin is useful for medicinal purposes and has been used in its natural form for centuries.
How is acetylsalicylic acid prepared from salicylic acid chemical reaction?
To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride. A small amount of a strong acid is used as a catalyst which speeds up the reaction. In this experiment, phosphoric acid will be used as the catalyst. The excess acetic acid will be quenched with the addition of water.
How is salicylic acid converted into aspirin?
For the preparation of aspirin, salicylic acid is reacted with an excess of acetic anhydride. Small amount of strong acid is used as a catalyst in these reactions which enhances the speed of reaction acid used is phosphoric acid. Excess acetic acid will be extinguished with the addition of water.
What is the action of acetic anhydride on salicylic acid?
Explanation: Aspirin is made from salicylic acid by an acetylation process in an acidic environment. In the presence of a few drops of strong sulphuric acid, salicylic acid reacts with acetic anhydride to create aspirin and a molecule of acetic acid.
How is salicylic acid produced?
Salicylic acid is produced commercially via the Kolbe-Schmitt process. Here phenol and sodium hydroxide are reacted to make sodium phenoxide. The phenoxide is contacted with CO2 to form sodium salicylate. The salicylate is acidified to give salicylic acid.
How does salicylic acid react with acetic acid?
To make acetylsalicylic acid, the -OH group of the salicylic acid reacts with acetic acid to produce the ester and water. This reaction, like most esterification reactions, is an equilibrium process that does not go to completion and will not produce 100\% yield unless the water is removed during the reaction.
What happens when salicylic acid reacts with acetic anhydride followed by acid hydrolysis?
The reaction for synthesis of acetylsalicylic acid is shown in the following figure. Salicylic acid, prepared from the hydrolysis of methylsalicylate is reacted with acetic anhydride producing the ester product, acetylsalicylic acid.
What kind of reaction is the conversion of salicylic acid to acetylsalicylic acid?
esterification reaction
Organic Synthesis Experiments The preparation consists of an esterification reaction catalyzed by acid (H2SO4 or H3PO4), where salicylic acid treated with acetic anhydride gives acetylsalicylic acid (aspirin). In this reaction, a hydroxyl group is converted to an ester, with acetic acid as a byproduct.