Can secondary structure be predicted?

Most commonly, the secondary structure prediction problem is formulated as follows: given a protein sequence with amino acids, predict whether each amino acid is in the α-helix (H), β-strand (E), or coil region (C).

How we can predict the secondary structure of proteins?

Secondary structure of the proteins can be used to predict the tertiary structure since predicting only with amino acid sequence may not be sufficient. The secondary structure of proteins is determined by the pattern of hydrogen bonding.

Is secondary structure of protein stable?

Secondary Structure The α-helix is a right-handed coiled strand. bond in the strand and the hydrogen of each N-H group four amino acids below it in the helix. The hydrogen bonds make this structure especially stable.

Is a protein secondary structure prediction tool?

A great number of software tools for protein structure prediction exist. Approaches include homology modeling, protein threading, ab initio methods, secondary structure prediction, and transmembrane helix and signal peptide prediction.

Can we predict a protein structure from its amino acid sequence?

Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence — that is, the prediction of its folding and its secondary, tertiary, and quaternary structure from its primary structure.

Which secondary structure of protein is more stable?

It has been shown that α-helices are more stable, robust to mutations and designable than β-strands in natural proteins, thus designing functional all-α proteins is likely to be easier that designing proteins with both helices and strands; this has been recently confirmed experimentally.

Which of the following is not true about secondary protein structure?

2. Which of the following is not true about secondary protein structure? Explanation: The hydrophilic/hydrophobic character of amino acid residues is important to protein tertiary structure rather than to secondary structure. Explanation: Secondary structure of proteins is of two forms α-helix and β-pleated structures.

What stabilizes secondary protein structure?

Secondary Structure This structure resembles a coiled spring and is secured by hydrogen bonding in the polypeptide chain. The second type of secondary structure in proteins is the beta (β) pleated sheet.

How do you identify secondary structures?

Secondary structure elements typically spontaneously form as an intermediate before the protein folds into its three dimensional tertiary structure. Secondary structure is formally defined by the pattern of hydrogen bonds between the amino hydrogen and carboxyl oxygen atoms in the peptide backbone.

Which one of the following is a secondary protein structure database?

OMIM is a secondary database.