What is the most common side effect of zoledronic acid?

Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported.

How long do the side effects of zoledronic acid last?

Symptoms of this reaction may include flu-like symptoms, fever, headache, chills, and bone, joint or muscle pain. These symptoms may begin during the first 3 days after you receive a dose of zoledronic acid injection and may last 3 to 14 days.

How long does zoledronic acid take to work?

It takes at least 7 days after a dose to get the full benefit of this drug. The dose may need to be repeated depending on your blood calcium levels. For the treatment of multiple myeloma and bone problems caused by the spread of cancer, this medication is usually given every 3 to 4 weeks or as directed by your doctor.

Does zoledronic acid cause bone pain?

Zoledronic acid can cause bone, joint and/or muscle pain that can be severe. This can occur from 1 day to several months after starting the medication. Report these symptoms to your provider, who can advise you on strategies to relieve the pain.

Does zoledronic acid make you tired?

Flu-like symptoms; mild fever sometimes accompanied by malaise, chills, fatigue and flushing. Usually occurs with first treatment with zoledronic acid only.

Does zoledronic acid affect kidneys?

Zoledronic acid is associated with reports of renal impairment and renal failure, especially in patients with pre-existing renal dysfunction or other risk factors. Renal function should be measured before each dose, and patients should be adequately hydrated before treatment.

How safe is zoledronic acid?

Zoledronic acid had an acceptable safety profile; no adverse events were considered to be drug related. Treatment with ZA improved bone health by enhancing bone mineral density and reducing bone turnover, even in high-risk patients.

Does zoledronic acid cause weight gain?

Tell your doctor if you have serious side effects of Reclast including urinating less than usual or not at all; drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting, swelling, weight gain, shortness of breath, muscle spasms, numbness or tingling (especially around your mouth).

Does zoledronic acid affect the heart?

Patients treated with zoledronic acid had a higher risk for heart failure, among other cardiovascular conditions, according to a study presented at the American Society for Bone and Mineral Research (ASBMR) 2017 Annual Meeting held September 8-11 in Denver, Colorado.

What is a zoledronic acid infusion?

Zoledronic acid (ZOL) is an intravenous bisphosphonate that is given once yearly for the treatment of osteoporosis via a medically supervised 15-minute infusion. This ensures compliance for a full 12 months.

How much does a zoledronic acid infusion cost?

The cost for zoledronic acid intravenous solution (4 mg/5 mL) is around $46 for a supply of 5 milliliters, depending on the pharmacy you visit….Intravenous Solution.

Does zoledronic acid affect your immune system?

It still remains unclear what role zoledronic acid plays. “We know it affects the immune system and inflammation, and both of those are important in fighting infection and cardiovascular disease,” Colon-Emeric says.

What are the side effects of kojic acid?

Increased Sensitivity. Use of kojic acid can lead to an increased sensitivity of skin.

Do people know about serious Reclast side effects?

Common side effects of Reclast include: hypophosphatemia, hypokalemia, and hypomagnesemia. Other side effects include: hypocalcemia. See below for a comprehensive list of adverse effects. Along with its needed effects, zoledronic acid (the active ingredient contained in Reclast) may cause some unwanted effects.

Is it a side effect from Reclast?

Common side effects of Reclast include: nausea, tiredness, flu-like symptoms (e.g., fever, chills, muscle/joint aches), cough, dizziness, headache, vision problems, diarrhea, constipation, joint or muscle pain, or injection site reactions (pain, redness, swelling).

What are the side effects of hyaluronic acid?

Topical application. Topical application of hyaluronic acid moisturizes the skin and reduces wrinkles; it is safe and effective for all skin types.