Why do eukaryotes need three different RNA polymerases?
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Why do eukaryotes need three different RNA polymerases?
In addition, five subunits of the eukaryotic RNA polymerases are common to all three different enzymes. Consistent with these structural similarities, the different eukaryotic polymerases share several functional properties, including the need to interact with other proteins to appropriately initiate transcription.
Why do prokaryotes have single RNA polymerase?
Prokaryotes use the same RNA polymerase to transcribe all of their genes. In E. Four of these subunits, denoted α, α, β, and β′ comprise the polymerase core enzyme. These subunits assemble every time a gene is transcribed, and they disassemble once transcription is complete.
Why would RNA polymerase in eukaryotes need to be different than in prokaryotes?
Eukaryotic promoters are much larger and more intricate than prokaryotic promoters. Instead of the simple σ factor that helps bind the prokaryotic RNA polymerase to its promoter, eukaryotes assemble a complex of transcription factors required to recruit RNA polymerase II to a protein coding gene.
Why more than one type of RNA polymerase is required for transcription in eukaryotes?
Specifically, in eukaryotes, transcription is achieved by three different types of RNA polymerase (RNA pol I-III). Because RNA pol II transcribes protein-encoding genes, it has been of particular importance to scientists who study the regulation of eukaryotic gene expression, and its function is well understood.
How do the number of RNA polymerases distinguish prokaryotes and eukaryotes?
Prokaryotes have only one RNA Polymerase, while eukaryotes have three (RNA Polymerases I, which transcribes rRNA; II, which transcribes mRNA; and III, which transcribes tRNA).
Do prokaryotes only have one RNA polymerase?
Prokaryotes have only one RNA Polymerase, while eukaryotes have three (RNA Polymerases I, which transcribes rRNA; II, which transcribes mRNA; and III, which transcribes tRNA). There are differences in initiation between prokaryotes and eukaryotes.
How many RNA polymerase are in eukaryotes?
three
In eukaryotic cells, three nuclear RNA polymerases (RNA pols) carry out the transcription from DNA to RNA, and they all seem to have evolved from a single enzyme present in the common ancestor with archaea.
Do prokaryotes use RNA polymerase?
Both prokaryotic and eukaryotic transcriptions use a common enzyme, RNA polymerase, to transcribe DNA into RNA. Prokaryotes utilize one RNA polymerase for all transcription of types of RNA.
Which RNA polymerase is in prokaryotes?
Prokaryotes utilize one RNA polymerase for all transcription of types of RNA. In contrast, eukaryotes utilize three slightly different RNA polymerases: RNA polymerase I, RNA polymerase II, and RNA polymerase III (8).
Do prokaryotes need transcription factors?
Eukaryotes have three types of RNA polymerases, I, II, and III, and prokaryotes only have one type. Eukaryotes form and initiation complex with the various transcription factors that dissociate after initiation is completed. There is no such structure seen in prokaryotes. These events do not occur in prokaryotes.