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Can inflammation cause autoimmune disorders?

Can inflammation cause autoimmune disorders?

Recently, increasing evidences have shown that the abnormal inflammatory response is closely associated with many chronic diseases, especially in autoimmune diseases, including rheumatoid arthritis (RA), inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), gout, and diabetes [1–3].

What autoimmune disease has inflammation?

1. Rheumatoid Arthritis – Rheumatoid arthritis is a chronic inflammation of the lining of the joints, leading to pain and swelling typically in the hands and feet. It can affect anyone, but is most prevalent in women over 40.

What are autoimmune diseases caused by?

The exact cause of autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger changes that confuse the immune system. This may happen more often in people who have genes that make them more prone to autoimmune disorders.

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Is autoimmune and inflammatory disease the same thing?

Summary. Autoimmune diseases involve the adaptive immune system, while autoinflammatory diseases involve the innate immune system.

What viruses cause autoimmune?

Table 1

Autoimmune Disease Virus Proposed Mechanism
Autoimmune myocarditis Coxsackievirus B3 Bystander activation
Autoimmune thyroiditis Human herpesvirus 6A (HHV-6A)
Cryoglobulinemia Hepatitis C virus
Encephalitis (Human herpes encephalitis) Herpes simplex virus Molecular mimicry

How do you treat auto inflammatory disease?

The therapy with the most important and widespread effect on autoinflammatory disorders is colchicine, a medication extracted from the meadow saffron and used since the first century for rheumatologic diseases, such as gout.