How will the absence of ribosomes in RER will affect its function?

Inside the cells are specialized structures called organelles that help them perform certain functions. Ribosomes are organelles that create proteins. A single cell may contain up to 10 million ribosomes. Without these ribosomes, cells would not be able to produce protein and would not be able to function properly.

Does the RER have ribosomes attached to its outer surface?

Rough endoplasmic reticulum, (RER), has large numbers of ribosomes attached to the outer surfaces of the lamella membranes. These ribosome-rich areas play an important role in the production, storage and export of proteins.

Why are ribosomes present on RER?

Ribosomes on the rough endoplasmic reticulum are called ‘membrane bound’ and are responsible for the assembly of many proteins. This process is called translation. Certain cells of the pancreas and digestive tract produce a high volume of protein as enzymes.

What happens ribosome malfunction?

The researchers found that the defective ribosomes tend to make a specific kind of mistake when translating the genetic code. This mistake changes specific patterns of gene expression in cells, consistent with changes that can lead to cancer. The mistakes make an already unstable set of molecules even more unstable.

Why does RER appear rough?

Rough Endoplasmic Reticulum (RER) appears rough because of the presence of ribosomes on it. Ribosomes are sites for biological protein synthesis. Polyribosomes are aggregation of several ribosomes held together by a string of mRNA.

What happens in the RER?

rough endoplasmic reticulum (RER), series of connected flattened sacs, part of a continuous membrane organelle within the cytoplasm of eukaryotic cells, that plays a central role in the synthesis of proteins.

How are vesicles moved from one organelle to another?

Vesicular transport between organelles consists of three steps. First, vesicles bud from one organelle (e.g ER). The vesicle must then be targeted to the appropriate organelle (e.g Golgi). Finally, the vesicle must fuse with the target organelle to mix its contents with the contents of the target organelle.

What is the main function of the ribosome?

A ribosome is a cellular particle made of RNA and protein that serves as the site for protein synthesis in the cell. The ribosome reads the sequence of the messenger RNA (mRNA) and, using the genetic code, translates the sequence of RNA bases into a sequence of amino acids.