What are the symptoms of polycythemia rubra vera?

Symptoms

• Itchiness, especially after a warm bath or shower.
• Numbness, tingling, burning, or weakness in your hands, feet, arms or legs.
• A feeling of fullness soon after eating and bloating or pain in your left upper abdomen due to an enlarged spleen.
• Unusual bleeding, such as a nosebleed or bleeding gums.

Is there a cure for polycythemia rubra vera?

There’s no cure for polycythemia vera. Treatment focuses on reducing your risk of complications. These treatments may also ease your symptoms.

Is Polycythaemia Vera a rare disease?

Polycythemia vera is a rare blood disorder in which there is an increase in all blood cells, particularly red blood cells. The increase in blood cells makes the blood thicker.

Is polycythemia vera benign or malignant?

Polycythemia vera is caused by a malignant change in the genetic material (DNA) within a single cell of the bone marrow (clonal disorder). Bone marrow is the soft, spongy material found inside bone where most blood cell production occurs. The underlying reason why this malignant change occurs is unknown.

What does Jak 2 positive mean?

A positive JAK2 V617F mutation test, along with other supporting clinical signs, means it is likely that the person tested has an MPN. Other testing, such as a bone marrow biopsy, may need to be performed to determine which MPN the person has and to evaluate its severity.

Is polycythemia vera a type of leukemia?

In rare cases, polycythemia vera may eventually progress into a form of leukemia known as acute myeloid leukemia.

Is Polycythemia rubra vera inherited?

Most cases of polycythemia vera are not inherited. This condition is associated with genetic changes that are somatic, which means they are acquired during a person’s lifetime and are present only in certain cells. In rare instances, polycythemia vera has been found to run in families.