Why are some mutation more harmful than others?

Because an insertion or deletion results in a frame-shift that changes the reading of subsequent codons and, therefore, alters the entire amino acid sequence that follows the mutation, insertions and deletions are usually more harmful than a substitution in which only a single amino acid is altered.

Why are some mutations more common than others?

Rather, some occur more frequently than others because they are favored by low-level biochemical reactions. These reactions are also the main reason why mutations are an inescapable property of any system that is capable of reproduction in the real world.

Which mutation causes the most harm?

Insertion or deletion, which leads to frameshift mutation is more damaging. It causes changes in the subsequent amino acid sequences in a polypeptide chain. Point mutation only alters one amino acid, whereas frameshift mutation alters the whole sequence of amino acids following the mutation.

Why do some mutations not affect the organism?

Some mutations don’t have any noticeable effect on the organism. This can happen in many situations: perhaps the mutation occurs in a stretch of DNA with no function, or perhaps the mutation occurs in a protein-coding region, but does not affect the amino acid sequence of the protein.

What are some disadvantages of mutations?

Harmful mutations may cause genetic disorders or cancer. A genetic disorder is a disease caused by a mutation in one or a few genes. A human example is cystic fibrosis. A mutation in a single gene causes the body to produce thick, sticky mucus that clogs the lungs and blocks ducts in digestive organs.

Which type of mutations are the least harmful to an organism *?

Some mutations have no impact on an organism; these are known as silent mutations. Point mutations are those mutations that affect a single base pair. The most common nucleotide mutations are substitutions, in which one base is replaced by another.