What antibody is detected by RPR?
What antibody is detected by RPR?
Non-treponemal antibodies are detected by the rapid plasma reagin (RPR) assay, which is typically positive during current infection and negative following treatment or during late/latent forms of syphilis. For prenatal syphilis screening, the syphilis IgG test (SYPGN / Syphilis Total Antibody, Serum) is recommended.
Does RPR test for chlamydia?
The STD Panel is a comprehensive panel of 4 blood tests (HIV, Hepatitis, RPR, HSV-1/HSV-2) and a cervical swab (Gonnorhea/Chlamydia). If the specific STD risk is known, you may choose one or more individual tests based upon this knowledge – Please see the STD Testing Information sheet.
How accurate is an RPR test?
How soon various syphilis tests can be done—and their accuracy
| The earliest the test can be done —— Accuracy | |
|---|---|
| RPR | 2–3 weeks after exposure Accuracy: 86\% |
| VDRL | 3–6 weeks after exposure Accuracy: 78\% |
| FTA-ABS | 3–4 weeks after exposure Accuracy: 84\% |
| TPPA | 3–4 weeks after exposure Accuracy: 88\% |
What if RPR is reactive?
If the rapid plasma reagin (RPR) screen is reactive, then the RPR titer will be performed at an additional charge. If the RPR screen is nonreactive, then syphilis antibody Treponema pallidum particle agglutination testing will be performed at an additional charge.
Is RPR a Treponemal?
Therefore, VDRL or RPR results are confirmed by a Treponema pallidum-specific antibody test, such as Treponema pallidum particle agglutination assay (TP-PA).
Does RPR detect latent syphilis?
Initial screening for syphilis is performed with one of the nontreponemal antibody tests, the VDRL test or the reactive plasma reagin (RPR) test….Causes of False-Positive Serologic Tests for Syphilis.
| Nontreponemal causes | |
|---|---|
| Acute condition (< 6 months) | |
| Pneumococcal | |
| Mycoplasma | |
| Hepatitis |
How is RPR test different from the Vdrl test?
The rapid plasma reagin (RPR) test uses the same antigen as VDRL, but the antigen is bound to a carbon particle to allow visualization of the reaction without a microscope. VDRL or RPR titers are monitored to document response to therapy. RPR titers are frequently higher than VDRL titers.