What is stronger than 2-Chlorobutanoic acid?
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What is stronger than 2-Chlorobutanoic acid?
The position of substituent also has an important role in the acidic strength of carboxylic acid. For example, comparison of 2-chlorobutanoic acid, 3-chlorobutanoic acid, and 4-chlorobutanoic acid shows that 2-chlorobutanoic acid is the strongest one and 4-chlorobutanoic acid is the weakest one.
Why is 2 Chloropropanoic acid stronger than 3-Chloropropanoic acid?
In2-chloropropanoic acid Cl is at 2nd position of numbering in chain and therefore, the -inductive effect is distance dependent. The distance to -COOH group for Cl is less than in 3-chloropropanoic acid and hence it has more -I effct which makes it more stable and stronger.
Is 4-Chlorobutanoic acid a strong acid?
Yes, according to me 2-chlorobutanoic acid is a stronger acid than 3-chlorobutanoic acid. In 3-chlorobutanoic acid, the effect is weaker as the chlorine atom is farther away………….
What is the pKa value of 3-Chlorobutanoic acid?
Accuracy of Prediction of pKa (Home)
| Molecule | Exp. pKa | Calc’d pKa |
|---|---|---|
| 3-Chlorobutanoic acid | 4.05 | 4.28 |
| 3-Chlorophenol | 8.78 | 8.96 |
| 3-Chloropropanoic acid | 3.98 | 4.29 |
| 4-Chlorobutanoic acid | 4.53 | 4.71 |
Which of the following acids are more acidic than propanoic acid?
So, acetic acid is more acidic than propanoic acid.
Why is 2 Chlorobutanoic acid stronger than 3-Chlorobutanoic acid?
In 2-chlorobutanoic acid substituent chloro is closer to the C-O-H(no. of sigma bond is less from C-O-H to Cl) bond and -I effect (polarization of bond) is higher as compared to 3-chlorobutanoic acid. Therefore H remove easily as proton in 2-chlorobutanoic acid and hence it is stronger acid.
Why is 2 Chlorobutanoic acid stronger than butanoic acid?
This is probably because the electronegative chlorine atom is closer to the -COOH (carboxylic acid) group and thus exerts a stronger (-) inductive effect and helps in the removal of proton (+H). In 3-chlorobutanoic acid, the effect is weaker as the chlorine atom is farther away.
What is the structure of 3-Chlorobutanoic acid?
3-chlorobutanoic acid
| Compound number: | MolPort-001-792-261 |
|---|---|
| IUPAC traditional: | 3-chlorobutanoic acid |
| SMILES: | CC(Cl)CC(O)=O |
| InChI key: | XEEMVPPCXNTVNP-UHFFFAOYSA-N |
| Molecular formula: | C4H7ClO2 |
What is the Ka of 4 Chlorobutanoic acid?
| C4H7CIO2 | 2-Chlorobutanoic acid | RT |
| C4H7CIO2 | 3-Chlorobutanoic acid | RT |
| C4H7CIO2 | 4-Chlorobutanoic acid | RT |
| C4H7NO2 | 4-Cyanobutanoic acid | 25 |
| C4H7NO3 | N-Acetylglycine | 25 |