Why is verrucous carcinoma called carcinoma?

In spite of being called a ‘carcinoma’, the strict definition of VC is that these tumors lack dysplastic cytologic features, and that there is no invasion by the tumor cells through the basement membrane.

Is basal cell carcinoma the same as carcinoma in situ?

The characteristics and stages of basal cell carcinoma are: Stage 0: Also called carcinoma in situ, cancer discovered in this stage is only present in the epidermis (upper layer of the skin) and has not spread deeper to the dermis.

What is verrucous carcinoma?

Verrucous carcinoma is a relatively uncommon, locally aggressive, clinically exophytic, low-grade, slow-growing, well-differentiated squamous cell carcinoma with minimal metastatic potential.

What is the difference between verrucous carcinoma and squamous cell carcinoma?

Verrucous carcinoma is a rare variant of squamous cell carcinoma, which in itself is a form of non-melanoma skin cancer. While squamous cell carcinoma can appear almost anywhere on the body, verrucous carcinoma is more localized, often appearing in specific areas.

Is Verrucous carcinoma premalignant?

Verrucous hyperkeratosis (VH), verrucous carcinoma (VC) and the relentless, truly pre-malignant variant proliferative verrucous leukoplakia often exhibit lichenoid histologic features that may create a diagnostic dilemma for pathologists.

What is carcinoma in situ?

Carcinoma in situ (CIS) is a group of abnormal cells that are found only in the place where they first formed in the body (see left panel). These abnormal cells may become cancer and spread to nearby normal tissue (see right panel).

What is a carcinoma cell?

Carcinoma is a type of cancer that starts in cells that make up the skin or the tissue lining organs, such as the liver or kidneys. Like other types of cancer, carcinomas are abnormal cells that divide without control. They are able to spread to other parts of the body, but don’t always.

Is verrucous carcinoma cancerous?

Verrucous carcinoma is an uncommon cancer that often develops in an area of extreme irritation or inflammation with symptoms of cauliflower-like lesions.

How is verrucous carcinoma diagnosed?

A skin biopsy is always required for definitive diagnosis of verrucous carcinoma, despite the fact that the diagnosis is suspected strongly on clinical grounds. Biopsy is performed routinely in the physician’s office using a local anesthetic.

Is Verrucous carcinoma benign?

Verrucous carcinoma (VC) of oral cavity is a rare variant of well-differentiated squamous cell carcinoma and squamous papilloma is a benign proliferation of the stratified squamous epithelium, which results in a papillary or verrucous exophytic mass.

Is Verrucous carcinoma HPV?

Verrucous carcinoma of the genitalia (giant condyloma of Buschke-Löwenstein) is a low-grade, locally invasive squamous cell carcinoma that is associated with HPV types 6 and 11 and should be considered in the differential diagnosis of lesions greater than 1 cm in diameter.