Questions

How is chromhidrosis caused?

How is chromhidrosis caused?

Causes of chromhidrosis A pigment called lipofuscin is commonly associated with chromhidrosis. Lipofuscins are yellow-brown pigment granules made of fat-like residues. Certain activities such as hot showers and friction against the skin increase the likelihood of discolored sweat in people with chromhidrosis.

What are the symptoms of chromhidrosis?

Chromhidrosis is a disorder of the sweat glands that manifests with colored sweat on the face, in the underarms, or on the areola of the breasts (the darker circle of skin around the nipples). Sweat may be yellow, green, blue, brown, or black.

How do you get rid of chromhidrosis?

Apocrine chromhidrosis has no fully satisfactory cure or treatment. Patients can manually or pharmacologically empty the glands to achieve a symptom-free period of about 48-72 hours or until the glands replenish the pigment. BOTOX® injections have been attempted in 5 cases of chromhidrosis, with mixed results.

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How is chromhidrosis diagnosed?

The diagnosis is mainly a clinical one. The diagnosis of apocrine chromhidrosis can be confirmed by the demonstration of an increased number of lipofuscin granules in chromhidrotic apocrine cells on skin biopsy. Chromhidrosis should be differentiated from pseudochromhidrosis and alkaptonuria.

What drugs can cause chromhidrosis?

Eccrine chromhidrosis is due to water-soluble coloured dyes and other chemicals being excreted in the eccrine sweat. Examples include: Ingestion of medications, metals, and dyes including tartrazine-coated bisacodyl laxatives, quinine, rifampicin, clofazimine, methylene blue, mercury, and copper.

Is chromhidrosis serious?

There are a few possible causes of chromhidrosis, depending on the type. In a person with apocrine chromhidrosis, lipofuscin causes discoloration as part of the natural process of creating sweat. Certain situations stimulate the apocrine glands and make this discoloration more likely to occur: friction against the skin.

What kind of toxins do you sweat out?

The body does appear to sweat out toxic materials — heavy metals and bisphenol A (BPA), a chemical found in plastics, for instance, have been detected in sweat.

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What drugs make you hot sweaty?

Drugs that induce hyperhidrosis, or sweating in excess of that needed to maintain thermoregulation, can cause patient discomfort and embarrassment, and include cholinesterase inhibitors, selective serotonin reuptake inhibitors, opioids and tricyclic antidepressants.

Can sweat bleach sheets?

You can’t reverse bleaching damage. If they’re sweat or oil stains, a good detergent (we recommend Tide) can get them out. If you haven’t washed them yet, try pretreating the stains, wash on hot, and don’t dry them until the stains are out to your satisfaction. But yeah, you might just have to stick to white sheets.

What drugs can cause Chromhidrosis?