How much propofol does it take to die?

But 50 milligrams of propofol for a person with Jackson’s slender frame is typically far from lethal, says Hector Vila Jr., MD, a Tampa, Fla., anesthesiologist and chairman of the Ambulatory Surgery Committee for the American Society of Anesthesiologists.

Can you die from propofol?

Of the 38 cases, 14 (37\%) were fatal. Twelve of these deaths occurred in medical professionals, nine of whom were anesthesia providers. Most of those deaths now are thought to have occurred because of the rapidity of propofol injection which led to apnea and death.

Can propofol stop your heart?

Propofol displays both pro- and anti-arrhythmic effects in a concentration-dependent manner. Data indicate that propofol can convert supraventricular tachycardia and ventricular tachycardia and may inhibit the conduction system of the heart.

How much propofol can you bolus?

Most patients will require 1.5 – 4.5 mg propofol/kg body weight/h. The infusion may be supplemented by bolus administration of 10 – 20 mg (1 – 2 ml Propofol) if a rapid increase of the depth of sedation is required.

How much propofol did MJ take?

Toxicology results indicated that Jackson was given 40 milligrams – not four – in a series of 10 doses, he said. Although the defense recently abandoned the theory that Jackson may have swallowed propofol, the prosecution still worked to use its old theory to discredit Dr.

Why did MJ take propofol?

The 60 nights of propofol infusions Dr. Conrad Murray said he gave Jackson to treat his insomnia is something a sleep expert says no one had ever undergone. Jackson was exhibiting were consistent with what someone might expect to see of someone suffering from total sleep deprivation over a chronic period,” Dr.

Can propofol cause stroke?

Propofol-Induced Hypertriglyceridemia as a Cause of Stroke Elevated serum triglycerides (TGs) are associated with increased long-term risk of ischemic stroke.

What does propofol sedation feel like?

Patients sedated with propofol rarely complain of feeling “drugged” and more often remark that they feel as if they had a great nap. While fentanyl and other opioid-type drugs may cause nausea, particularly at higher doses, this is rare with propofol.

Can propofol cause long-term effects?

Conclusion: The limited data available suggest that long-term infusion of propofol is a practical alternative to use of standard agents for sedation of intubated patients. Adverse effects such as cardiovascular depression, respiratory depression, and hypertriglyceridemia may limit the routine use of propofol.