What is a peptidomimetic?

Peptidomimetics are compounds whose essential elements (pharmacophore) mimic a natural peptide or protein in 3D space and which retain the ability to interact with the biological target and produce the same biological effect.

What are peptidomimetic inhibitors?

A peptidomimetic is a small protein-like chain designed to mimic a peptide. They typically arise either from modification of an existing peptide, or by designing similar systems that mimic peptides, such as peptoids and β-peptides. This can have a role in the development of drug-like compounds from existing peptides.

Why Peptidomimetics are needed for drug discovery?

The art of transforming peptides into drug leads is still a dynamic and fertile field in medicinal chemistry and drug discovery. Peptidomimetics can respond to peptide limitations by displaying higher metabolic stability, good bioavailability and enhanced receptor affinity and selectivity.

What is a peptidomimetic Mcq?

Question 6. What is a peptidomimetic? a) A peptide lead compound that mimics the action of an endogenous neurotransmitter or hormone.

What are peptides and amino acids?

A peptide is a short chain of amino acids. Peptides are generally considered to be short chains of two or more amino acids. Meanwhile, proteins are long molecules made up of multiple peptide subunits, and are also known as polypeptides. Proteins can be digested by enzymes (other proteins) into short peptide fragments.

Which of the following descriptions most accurately describes binding sites and binding regions?

21) Which of the following descriptions most accurately describes binding sites and binding regions? Feedback: The binding site is an area of the receptor into which a drug or a natural chemical messenger can bind. A binding region is on a drug whereas a binding site is on a macromolecular target.

What is meant by binding site Mcq?

What is meant by a binding site? a) The area of a macromolecular target that is occupied by a drug when it binds.

What are the 4 main regulatory proteins that drugs are likely to interact with?

The drug-protein interactions were then categorized into four subgroups: carrier, enzyme, target and transporter.

What are peptides used for?

Peptides are sold in dietary supplements including pills or protein shakes. They claim to help you build muscle, boost weight and fat loss, and help with muscle recovery.

What is the meaning of binding site?

In biochemistry and molecular biology, a binding site is a region on a macromolecule such as a protein that binds to another molecule with specificity.

What is meant by a binding sites?

In biochemistry and molecular biology, a binding site is a region on a macromolecule such as a protein that binds to another molecule with specificity. The binding partner of the macromolecule is often referred to as a ligand.