What is the difference between hnRNA and mRNA?

The key difference between hnRNA and mRNA is that hnRNA is the unprocessed premature mRNA transcript that contains introns while mRNA is the processed RNA that does not contain introns. Therefore, hnRNA is synthesized from a DNA template, and it is a newly formed RNA prior to processing.

What is the function of heterogeneous nuclear RNA?

hnRNP E1 is ubiquitously expressed and functions in regulating major steps of gene expression, including pre-mRNA processing, mRNA stability, and translation.

What is heterogeneous nuclear RNA how it is converted into functional mRNA?

Heterogeneous nuclear RNA(hnRNA) is the precursor of mRNA and is transcribed by RNA polymerase II. The primary transcripts contain both the exons and the introns and are non-functional. Hence, it is subjected to a process called splicing where the introns are removed and exons are joined in a defined order.

Which form of RNA is most heterogeneous?

Messenger RNA (mRNA) mRNA is the most heterogeneous of the 3 types of RNA in terms of both base sequence and size. It carries complementary genetic code copied, from DNA during transcription, in the form of triplets of nucleotides called codons.

What is the difference between primary and mature RNA?

The initial product of transcription of a protein coding gene is called the pre-mRNA (or primary transcript). After it has been processed and is ready to be exported from the nucleus, it is called the mature mRNA or processed mRNA.

What is reminiscent antiquity?

Reminiscent of antiquity refers to the Introns which have no role in protein synthesis. Explanation: the dna sequence consists of Introns and exons.

Why is mRNA heterogeneous?

The fate and function of each cell depends on its protein composition. Therefore, accurate gene expression control is critical for proper cell functioning. Second, mRNA molecules originating from different genes can be differentially translated in a single cell, resulting in ‘intergenic’ translational heterogeneity.

How does HRNA become mRNA?

The hnRNA undergoes the following processes to form mRNA: (i) Capping: Addition of methyl guanosine triphosphate at 5′-end. (ii) Tailing: Addition of 200-300 adenylate residues at 3′-end. (iii) Splicing: Removal of introns and joining of exons.

What is heterogeneous RNA pre-mRNA contain?

Pre-mRNA is synthesized from a DNA template in the cell nucleus by transcription. Pre-mRNA comprises the bulk of heterogeneous nuclear RNA (hnRNA). Once pre-mRNA has been completely processed, it is termed “mature messenger RNA”, or simply “messenger RNA”.

What are three differences between pre-mRNA and mature mRNA?

The key difference between pre-mRNA and mRNA is that pre-mRNA is the first product of the transcribed gene and contains both non-coding sequences (introns) and coding sequences (exons) while mRNA is the second product of a transcribed gene which contains only coding sequences. Gene is the functional unit of heredity.

What is a Polysome and what is its function?

A polyribosome (or polysome or ergosome) is a group of ribosomes bound to an mRNA molecule like “beads” on a “thread”. The ability of multiple ribosomes to function on an mRNA molecule explains the limited abundance of mRNA in the cell. …