Which drugs are ototoxic?
Table of Contents
Which drugs are ototoxic?
List of Ototoxic Medications
- Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), including aspirin, ibuprofen, and naproxen.
- Certain antibiotics, including aminoglycosides.
- Certain cancer medications.
- Water pills and diuretics.
- Quinine-based medications.
What ototoxicity means?
What Is Ototoxicity? Certain medications can damage the ear, resulting in hearing loss, ringing in the ear, or balance disorders. These drugs are considered ototoxic. There are more than 200 known ototoxic medications (prescription and over-the-counter) on the market today.
How do you treat ototoxicity?
Aminoglycoside antibiotics, platinum-based chemotherapeutic agents, loop diuretics, macrolide antibiotics, and antimalarials are the commonly used ototoxic drugs [2] with well-documented efficacy against various infections and malignancies in children and adults.
What does ototoxicity feel like?
As your ototoxicity becomes worse, the sounds become louder. You may feel a pressure or fullness in your head or ears, like you have a cold. You may notice a loss of hearing, or your existing hearing loss may become worse. You might feel like the room is spinning around you, or that you are spinning.
What are signs of ototoxicity?
What Are the Signs & Symptoms of Ototoxicity?
- no problems.
- minimal hearing loss but not notice a problem.
- “ringing in the ears” (tinnitus).
- major problems with balance.
- hearing problems, usually in both ears (called bilateral hearing loss).
- profound hearing loss (deafness)
Is ibuprofen ototoxic?
While experts have long known that high doses of aspirin can damage hearing, they’ve recently discovered that even moderate doses can be ototoxic. Ditto for other nonsteroidal anti-inflammatory drugs such as naproxen (Aleve), ibuprofen (Advil) and diclofenac (Voltaren).
Is paracetamol ototoxic?
In large doses, paracetamol is both nephrotoxic and hepatotoxic, and this toxicity may arise through the production of free radicals. Recently, there has been a revival of interest in the hypothesis that aminoglycoside antibiotics are ototoxic because they facilitate free-radical production.
How do you know if you have ototoxicity?
What are common signs of ototoxicity?
- Ringing or buzzing sounds in ears (tinnitus)
- Dizziness/loss of balance.
- Change in hearing.
- Hearing loss usually happens first in the very high pitches (frequencies) that are not important for speech and language but if undetected this can progress to affect the speech frequencies.
Which of the following is a common symptom of ototoxicity?
Signs and symptoms of hearing loss may include: Muffling of speech and other sounds. Difficulty understanding words, especially against background noise or in a crowd. Trouble hearing consonants.
Does ibuprofen cause ototoxicity?
Ibuprofen Nonsteroidal anti-inflammatory drugs (NSAIDs) such as Ibuprofen which can be found in Advil, can cause hearing loss if used over a long period of time.