Why cefoperazone is combined with sulbactam?

Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

What is the use of cefoperazone and sulbactam injection?

Cefoperazone/sulbactam is a combination drug used as an antibiotic. It is effective for the treatment of urinary tract infections. It contains cefoperazone, a β-lactam antibiotic, and sulbactam, a β-lactamase inhibitor, which helps prevent bacteria from breaking down cefoperazone.

What is the difference between cefoperazone and ceftriaxone?

When antibiotic, administrative, and laboratory costs were calculated, cefoperazone was slightly less expensive than ceftriaxone. Both cefoperazone and ceftriaxone are effective therapy for the treatment of nosocomial pneumonia.

How do you give cefoperazone sulbactam?

Adult: Ratio of sulbactam:cefoperazone is 1:1. Doses are expressed in terms of cefoperazone. Mild to moderate infections: 1-2 g daily, given in equally divided doses every 12 hours. Severe infections: Up to 4 g daily, given in equally divided doses every 12 hours; max dose of sulbactam: 4 g daily.

What does cefoperazone treat?

Because of its antimicrobial spectrum, cefoperazone is used to treat lower respiratory tract infections, GU tract infections, skin infections, and septicemia and for surgical prophylaxis. Cefoperazone appears effective and safe during pregnancy for the treatment of acute infections.

What is cefoperazone used for?

Cefobid (sterile cefoperazone) is a cephalosporin antibiotic used to treat infections caused by bacteria.

Is cefoperazone a sulbactam?

General information. Cefoperazone-sulbactam (CEF/SUL) is a third generation cephamycin beta-lactamase inhibitor combination that has a broad spectrum of activity making it an attractive option for the treatment of both hospital-acquired (HAP) and healthcare-associated pneumonia (HCAP).

What is the use of ceftriaxone and sulbactam injection?

Ceftriaxone & Sulbactam for Injection is indicated in infections caused by Ceftriaxone sodium- sensitive pathogens and may be used in the clinical settings in Sepsis, Meningitis, Abdominal Infections (e.g. Peritonitis, infection of the biliary tract), infections of the Bones, Joints, Soft tissue, Skin and of wounds.

Is cefoperazone an antibiotic?

Cefoperazone is a third-generation cephalosporin antibiotic, marketed by Pfizer under the name Cefobid. It is one of few cephalosporin antibiotics effective in treating Pseudomonas bacterial infections which are otherwise resistant to these antibiotics.

What class of drug is cefoperazone?

Cefoperazone injection belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth.

What is the role of sulbactam?

It works by stopping the growth of bacteria. Sulbactam is in a class of medications called beta-lactamase inhibitors. It works by preventing bacteria from destroying ampicillin. Antibiotics such as ampicillin and sulbactam injection will not work for colds, flu, or other viral infections.