How long can you take Dacogen?

Decitabine is repeated every 28 days. This is known as one cycle. Treatment is continued until decitabine is no longer working or it is stopped because of unacceptable side effects.

Is Dacogen a chemotherapy?

Dacogen is the trade name for decitabine. In some cases, health care professionals may use the trade name Dacogen when referring to the generic drug name decitabine. Drug type: Decitibine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.

Does Dacogen cause hair loss?

However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Hair loss. Constipation, diarrhea, stomach pain, upset stomach, throwing up, or feeling less hungry.

How effective is Dacogen?

Overall anticancer responses were achieved in 17\% of patients treated with decitabine, compared with 0\% in patients treated with supportive care. Hematologic (blood) improvement occurred in 12\% of patients treated with Dacogen, compared with 7\% of patients treated with supportive care.

What is dacogen used for?

This medication is used to treat a group of blood/bone marrow disorders (myelodysplastic syndromes-MDS) in which the bone marrow does not produce enough healthy blood cells. People with MDS may have problems such as infections, anemia, and easy bleeding/bruising. Decitabine is a chemotherapy drug.

What does decitabine treat?

Decitabine is used to treat myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells). Decitabine is in a class of medications called hypomethylation agents.

What is dacogen given for?

How often is dacogen given?

Administer DACOGEN at a dose of 15 mg/m2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Repeat cycles every 6 weeks upon hematologic recovery (ANC at least 1,000/µL and platelets at least 50,000/µL) for a minimum of 4 cycles. .

What is the difference between azacitidine and decitabine?

Multivariate analysis revealed that compared with azacitidine treatment, decitabine treatment is significantly associated with a higher ORR (P = 0.026) and longer PFS (P = 0.037). No significant differences were observed in the incidence of grade 3 or higher haematologic adverse events in response to the two HMAs.

Is decitabine a chemo drug?

DECITABINE (dee SYE ta been) is a chemotherapy drug. This medicine reduces the growth of cancer cells. It is used to treat adults with myelodysplastic syndromes.

How long does it take decitabine to work?

How long does it take for patients to respond to treatment? In the clinical study, the median time for patients to achieve some level of remission for either CR or CRh was 2 months (with a range of 0.8 to 4.2 months).

Does dacogen cause constipation?

Redness/pain/bruising at the injection site, nausea, constipation, diarrhea, vomiting, upset stomach, trouble sleeping, hair loss, or muscle/joint pain may occur.

https://www.youtube.com/watch?v=dd8vr_2zhGI