Is modafinil safe in the long-term?

The long-term safety of modafinil is not known. Modafinil affects an enzyme that may alter the blood concentration of some drugs such as opioids and some anti-viral medications. Check with your doctor for other drug interactions before taking modafinil.

Does modafinil make you smarter?

Modafinil does enhance alertness in people who are sleep-deprived, although it is unlikely to make you smarter. Think carefully before you take it for any unapproved indication, such as a study aid or to help you meet that deadline, especially if it has not been prescribed by a doctor.

Can you build tolerance to modafinil?

In humans, modafinil is efficient and well tolerated, with no evidence of tolerance developing during 40 weeks of treatment.

Can modafinil cause weight gain?

A 30-lb weight gain over a 6-month period occurred following discontinuation of modafinil. Reinstitution of modafinil resulted in a 10-lb. weight loss over a 6-week period. Conclusions: Modafinil treatment resulted in a significant weight loss in this patient, possibly due to reducing clozapine-associated fatigue.

Is modafinil good for ADHD?

Research studies have indicated that modafinil: May be significantly more effective in treating the symptoms of ADHD than placebo. May have comparable efficacy for treating ADHD to methylphenidate (e.g., Ritalin, Concerta) and fewer side effects.

Does modafinil have a crash?

Modafinil, in contrast to other stimulants, does not induce the same type of crash or depressive feelings after the drug wears off. It does however have some potential side effects—common to stimulants—including the following: Anxiety.

Does modafinil give you motivation?

These data support the hypothesis that modafinil increases motivation. Furthermore, the dopamine D1R may play a downstream role in mediating modafinil-induced increases in motivation. Thus studies reporting cognition-enhancing effects of modafinil may have been influenced by its ability to increase motivation.

Is modafinil a mood stabilizer?

Modafinil at a dosage of 100 to 200 mg/d has been shown to alleviate depressive symptoms when compared with placebo in adults with bipolar disorder across 6 weeks of treatment.

Does modafinil help with ADHD?