What is pleiotropy give example?

An example of pleiotropy is phenylketonuria, an inherited disorder that affects the level of phenylalanine, an amino acid that can be obtained from food, in the human body. Phenylketonuria causes this amino acid to increase in amount in the body, which can be very dangerous.

What is pleiotropy very short answer?

In genetics, Pleiotropy is defined as the expression of multiple traits by a single gene. Pleiotropy is derived from a Greek word meaning more ways. A simple example of a Pleiotropy is phenylketonuria is a disease. It is a genetic disorder caused by the low metabolism of the amino acid phenylalanine in the body cells.

What is called pleiotropy?

The term pleiotropy is derived from the Greek words pleio, which means “many,” and tropic, which means “affecting.” Genes that affect multiple, apparently unrelated, phenotypes are thus called pleiotropic genes (Figure 1).

What is pleiotropy class 12 biology?

Answer. 117.6k+ views. Hint: Pleiotropy is defined as the special condition when one gene is responsible for controlling two distinct phenotype traits and these traits are unrelated to each other in all ways. Pleiotropy is seen in different genetic disorders in human beings.

What is pleiotropic action?

Pleiotropic effects of a drug are actions other than those for which the agent was specifically developed. These effects may be related or unrelated to the primary mechanism of action of the drug, and they are usually unanticipated.

What is Phenocopy in genetics?

A phenocopy is a variation in phenotype (generally referring to a single trait) which is caused by environmental conditions (often, but not necessarily, during the organism’s development), such that the organism’s phenotype matches a phenotype which is determined by genetic factors.

What is pleiotropy Toppr?

Pleiotropy occurs when one gene influences multiple, seemingly unrelated phenotypic traits, an example being phenylketonuria, which is a human disease that affects multiple systems but is caused by one gene defect. Consequently, a mutation in a pleiotropic gene may have an effect on some or all traits simultaneously.

What is pleiotropy Class 12 shaala?

When a single gene controls two (or more) different traits it is called pleiotropic gene and the phenomenon is called pleiotropy or pleiotropism. The phenotypic ratio is 1:2 instead of 3:1 because of the death of recessive homozygote. Two different expressions are produced by a single gene.

What is pleiotropy PPT?

Introduction • Defination- Pleiotropism is defined as when one gene influences multiple, unrelated phenotypic traits • Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits • Mutation in a pleiotropic gene may have an effect on some or all traits • Mechanism of pleiotropy in most cases …

What is pleiotropic cytokine?

Cytokine pleiotropy is the ability of a cytokine to exert many different types of responses, often on different cell types, whereas cytokine redundancy refers to the fact that many different cytokines can induce similar signals.

What is linkage and crossing over?

Crossing over is the process of separation of genes between homologous pairs into various gametes. Linkage is the tendency of inheriting genes together on the same chromosome. Linkage occurs when two genes are closer to each other on the same chromosome. Crossing over may disrupt the gene groups made by linkage.