What is Tpha test for?

Treponema pallidum hemagglutination commonly known as TPHA is diagnostic test used to detect the dissolved amount of antibodies in the serum sample of a patient against the causative agents of syphilis. To be precise the TPHA test helps in the detection of Palladium antibodies via the hemagglutination method.

What is the difference between TPHA and RPR?

TPHA = Treponema pallidum haemagglutination test. RPR = Rapid plasma reagin.

Is Tpha confirmatory test for syphilis?

As described, there are two standard screening methods and two alternative confirmatory tests for the laboratory diagnosis of syphilis: VDRL (sensitivity = 86\%, specificity = 85\%); RPR (sensitivity = 78\%, specificity = 85\%); TPHA (sensitivity >95\%, specificity >99\%) and.

How accurate is TPHA test?

The positive predictive value (PPV) and negative predictive value (NPV) were 92.3 and 98.9\%, respectively. The agreement between TPHA and ELISA tests was nearly perfect with a kappa value of 0.96 (Table 3).

What is the normal range of TPHA test?

CSF abnormalities	Serum TPHA titre
CSF WBC count > 5/μl, n (\%)	6 (6)	19 (39)
Median (IQR)a	7 (7–7)	20 (11–41)
CSF TPHA titre ≥ 1:640, n (\%)	7 (7)	39 (80)
Median (IQR)a	1:640 (1:640–1:640)	1:2560 (1:1280–1:10,240)

Is Vdrl and RPR the same?

The rapid plasma reagin (RPR) test uses the same antigen as VDRL, but the antigen is bound to a carbon particle to allow visualization of the reaction without a microscope. VDRL or RPR titers are monitored to document response to therapy. RPR titers are frequently higher than VDRL titers.

How accurate is Tpha test?

Is VDRL a blood test?

The venereal disease research laboratory test (VDRL) is a blood test that can identify syphilis infections. Syphilis is one of the most common sexually transmitted infections (STIs). The Centers for Disease Control and Prevention (CDC) reported 115,045 new syphilis diagnoses during 2018.

Is VDRL test for syphilis?

The VDRL test is a screening test for syphilis. It measures substances (proteins), called antibodies, which your body may produce if you have come in contact with the bacteria that cause syphilis. Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand.

Is Vdrl a blood test?

The VDRL test Blood is generally drawn from a vein at the crease of the elbow or the back of the hand. This blood sample will then be sent to a laboratory and tested for the antibodies produced as a result of syphilis. The VDRL test doesn’t require you to fast or stop taking any medications.

What is the normal range of Tpha test?