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Why does pyridine undergoes nucleophilic substitution at 2 position?

Why does pyridine undergoes nucleophilic substitution at 2 position?

In contrast to benzene ring, pyridine efficiently supports several nucleophilic substitutions. The reason for this is relatively lower electron density of the carbon atoms of the ring.

Which position is preferred for nucleophilic substitution reaction in Nitroarenes?

Nucleophilic aromatic substitution mechanisms The SNAr mechanism is the most important of these. Electron withdrawing groups activate the ring towards nucleophilic attack. For example if there are nitro functional groups positioned ortho or para to the halide leaving group, the SNAr mechanism is favored.

Why pyridine is more reactive towards nucleophiles than benzene?

Answer: Pyridine is less reactive, than benzene toward electrophilic aromatic substitution, because nitrogen is more electronegative, than carbon and acts like an electron withdrawing group. Answer: Pyridine is more reactive than benzene because the presence of nitrogen enables pyridine to react with nucleophiles.

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Why electrophilic attack at the alpha position in pyrrole is preferred?

Whereas attack at the β-position produces an intermediate that can be described by only 2 resonance structures. Therefore, the intermediate formed by α attack is more stable and the activation energy leading to it will be reduced. Consequently, electrophilic attack at the α position in pyrrole is preferred.

Why furan undergoes the electrophilic substitution at C2 position?

Answer and Explanation: The furan undergoes electrophilic substitution on the 2nd position. The electrophilic substitution at C2 position gives more resonating structures than substitution at C3 position. More the resonating structure, the molecule is more stable, so the C2 attack prefers.

Which position is preferred for nucleophilic substitution reactions in Nitroarenes?

Nucleophilic aromatic substitution mechanisms Electron withdrawing groups activate the ring towards nucleophilic attack. For example if there are nitro functional groups positioned ortho or para to the halide leaving group, the SNAr mechanism is favored.